Faculty & Staff

Pamela J. Weathers

Publications

Peer-Reviewed (Refereed) Journal Articles

Liu CZ, Towler MJ, Medrano G, Dolan MC, CramerCL, Weathers PJ 2008/9 Production of mouse Interleukin-12 is greater in tobacco hairy roots grown in a mist reactor than in an airlift reactor. Biotechnol Bioengin. Accepted for publication.
Weathers, P.J., Wobbe, K.K., Wyslouzil, B.E. 2008 INVITED REVIEW – In vitro production of artemisinin: biosynthesis, regulation, and bioprocess development. In: Molecular Plant Cell-Based Bioprocessing (ed. Zhang, W, Springer, Dordrecht, The Netherlands. In press.
Weathers, P.J., Wyslouzil, B. E. 2008 INVITED. Alternate bioreactors: Mist. In: Encyclopedia of Cell Technology. (Ed. R.E. Spier, John Wiley & Sons, NY, NY) 2^nd edition. In press.
Arsenault PR, WobbeKK, Weathers PJ 2008 INVITED.Recent advances in artemisinin production through heterologous expression. Current Medicinal Chemistry. In press.
Sharaf-Eldin, MA, Elkholy S, Fernandez JA, Junge H, Cheetham RD, Guardiola JL, Weathers PJ 2008 Bacillus subtilis FZB24® affects flower quantity and quality of Saffron (Crocus sativus L.) Planta Medica, in press
Towler, M.J., Wyslouzil, B.E., Weathers, P.J. 2007 Using an aerosol deposition model to increase hairy root growth in a mist reactor. Biotechnology & Bioengineering,96:881-891.
Wang, Y., Weathers, P.J. 2007 Sugars proportionately affect artemisinin production. Plant Cell Reports. 26:1073-1081.
Towler, MJ,Weathers PJ 2007 Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. Plant Cell Reports 26:2129–2136.
Towler, M, Kim, YJ, Correll, M, Wyslouzil, B, Weathers, PJ. 2006. Design, development, and applications of mist bioreactors for micropropagation and hairy root culture. In: Plant Tissue Culture Engineering. Eds. Gupta, SD, Ibaraki, Y. Springer, The Netherlands. Pp. 119-134.
Weathers, P.J., Elkholy, S, Wobbe, K.K. 2006 Artemisinin: the biosynthetic pathway and its regulation in Artemisia annua, a terpenoid-rich species. In Vitro Cellular and Developmental Biology-Plant 42:309-317.
Weathers, PJ. Bunk, G, McCoy, MC 2005 The Effect of Phytohormones on Growth and Artemisinin Production in Artemisia annua Hairy Roots. In Vitro Cellular Developmental Biology Plant, 41:47-53.
Weathers, PJ, DeJesus-Gonzalez, L, Kim, YJ, Souret, FF, MJ Towler 2004 Alteration of biomass and artemisinin production in A. annua hairy roots by media sterilization method and sugars. Plant Cell Reports, 23:414-418.
Towler, M., Weathers, P. 2003 Adhesion of plant roots to poly-L-lysine coated polypropylene substrates. J. Biotechnology 101:147-155.
De Jesus-Gonzalez, L, Weathers, PJ 2003 Tetraploid Artemisia annua hairy roots produce more artemisinin than diploids. Plant Cell Reports 21:809-813.
Kim, YJ, Weathers, PJ, Wyslouzil, BE 2003 Growth dynamics of Artemisia annua hairy roots in three culture systems. Biotechnology and Bioengineering. 83:428-443.
Souret, F., Kim, Y., Wyslouzil, B., Wobbe, K., Weathers, P. 2003 Scale-up of Artemisia annua L. hairy root cultures produces complex patterns of terpenoid gene expression. Biotechnology and Bioengineering. 83:653-667.
Krushkal, J, Pistilli, M, Ferrell, KM, Souret, FF, Weathers, PJ 2003 Computational analysis of the evolution of the structure and function of 1-deoxy-D-xylulose-5-phosphate synthase, a key regulator of the mevalonate-independent pathway in plants. Gene. 313:127-138.
Kim, Y., Wyslouzil, B.E., Weathers, P.J. 2001 A comparative study of mist and bubble column reactors in the in vitro production of artemisinin. Plant Cell Reports 20:451-455.

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