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Cat. II
An introduction to the nature of biomedical engineering. Biomechanics,
materials and hemodynamics. Energy and mass transfer
systems. Membranes, artificial organs. Bioelectric signals,
instrumentation systems. Biological control and simulation.
The purpose of this course is to introduce the student to biomedical
engineering: i.e., the application of the principles and techniques of
engineering and physical science to biology and medicine. Guest
lecturers actively working in biomedical engineering will be
utilized.
Recommended background: Differential and integral calculus, ordinary
differential equations. Basic course in biology. Basic course in
physics.
This course will be offered in 1996-97 and in alternate years
thereafter.
Cat. II
This course emphasizes the applications of mechanics to describe the
material properties of living tissues. It is concerned with the
description and measurements of these properties as related to their
physiological functions. Emphasis on the interrelationship between
biomechanics and physiology in medicine, surgery, body injury and
prostheses.
Topics covered include: review of basic mechanics, stress, strain,
constitutive equations and the field equations, viscoelastic behavior,
and models of material behavior. The measurement and characterization
of properties of tendons, skin, muscles and bone. Biomechanics as
related to body injury and the design of prosthetic devices.
Recommended background: Differential and integral calculus, ordinary
differential equations, ME 2504, and familiarity with the concepts of
mechanics.
This course will be offered in 1996-97 and in alternate years
thereafter.
Cat. II
This course emphasizes the applications of fluid mechanics to
biological problems. The course concentrates primarily on the human
circulatory and respiratory systems. Topics covered include: blood
flow in the heart, arteries, veins and microcirculation and air flow
in the lungs and airways. Mass transfer across the walls of these
systems is also presented.
A background in continuum mechanics (ME 2504) and fluid mechanics
equivalent to ME 3602 is assumed.
This course will be offered in 1996-97 and in alternate years
thereafter.
Cat. II
A course specializing in material selection and special problems
associated with biomedical engineering.
Topics covered include: fundamentals of metals, plastics, and ceramics
and how they can be applied to biomedical applications. Case histories
of successful and unsuccessful material selections. Current literature
is the primary source of material.
Knowledge of introductory materials science is assumed.
This course will be offered in 1995-96 and in alternate years
thereafter (or more often depending on interest).
Origin and characteristics of bioelectric signals, recording electrodes. Biomedical amplifiers and signal processing. Chemical, pressure and flow transducers. Patient safety. Noninvasive monitoring techniques. Telemetry.
This course is concerned with the "hands-on" design of computer-based
medical instrumentation. Using specific instrumentation problems, the
specification, design, and evaluation of an "intelligent" instrument
is examined in detail. An actual "instrument" is implemented using a
commercial microcomputer development system. Important considerations
in small computer-based medical instrument design will be presented
including: analysis and use of medical transducers, real-time data
acquisition and programming, and common signal processing
techniques.
Prerequisite: Biomedical Instrumentation (BE 523),
analog and digital electronics.
Review of control theory with applications to biological control systems. Theory and operation of analog and hybrid computers. Development of mathematical models of selected biological control systems and the application of computer techniques in the simulation of these systems.
Application of information and communication theory to processing and
analysis of biological signals. Introductory digital signal processing
combined with a survey of adaptive, signal dependent processing
methods.
Prerequisites: basic signal analysis and controls.
Defines the functions required of a multicellular organism in order for it to sustain life and describes these in terms of physical and chemical principles. Topics covered which will prepare the engineer for more advanced work in a particular organ system. Included are diffusion, osmotic pressure, membrane potential, cellular transport, body fluid compartments, the circulation, the heart as a pump, respiration, gas transport by the blood, the composition of alveolar gas, urine formation by the kidneys, acid-base balance, signaling in the nervous system, the mechanics of muscle contraction, patterns of muscle.
A study of anesthesia, surgical techniques, and postoperative care in small laboratory animals. Anatomy and physiology of species used included as needed.
Overview of the physics of medical image analysis.
Topics covered
include X-ray tubes, fluoroscopic screens, image intensifiers; nuclear
medicine; ultrasound, computer tomography; nuclear magnetic resonance
imaging. Image quality of each modality is described mathematically,
using linear systems theory (Fourier transforms, convolutions).
Prerequisite: EE 3301 or equivalent.
(Prerequisites: Differential and integral calculus, ordinary differential equations, organic chemistry recommended). This course emphasizes the applications of Fourier transform nuclear magnetic resonance (FTNMR) imaging and spectroscopy in medicine and biology. Course topics include: Review of the basic physical concepts of NMR (including the Bloch equations), theoretical and experimental aspects of FTNMR, theory of relaxation mechanisms in FTNMR, instrumentation for FTNMR, NMR imaging techniques (point, line, plane, and volume methods), and in vivo NMR spectroscopy (including volume localization techniques).