Title page for E-project-033007-121423

Project Type MQP

Submission date 2007-03-30

Authors
Daniel V Filipe, BE
Nicholas S McBride, BE
Megan K Murphy, BE
Deep Arjun Singh, BE

URN E-project-033007-121423

Title Design of a Composite Scaffold for Myocardial Regeneration Following Infarction

Advisors
Pins, George D, BE
Gaudette, Glenn R, BE

Availability unrestricted

Abstract
The heart does not regenerate new tissue when myocardium dies following acute myocardial infarction. We have undertaken an iterative process to design and test a patch that will replace infarcted tissue and induce myocardial regeneration to improve heart function. The result is a composite scaffold design composed of an endocardial patch to provide mechanical stability and an injectable filler material to provide a regenerative scaffold environment. This project provides a vital first step toward a final solution for myocardial regeneration.

Files
CardiacScaffoldMQPReport.pdf

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Project Type	MQP
Submission date	2007-03-30
Authors	Daniel V Filipe, BE Nicholas S McBride, BE Megan K Murphy, BE Deep Arjun Singh, BE
URN	E-project-033007-121423
Title	Design of a Composite Scaffold for Myocardial Regeneration Following Infarction
Advisors	Pins, George D, BE Gaudette, Glenn R, BE
Availability	unrestricted
Abstract The heart does not regenerate new tissue when myocardium dies following acute myocardial infarction. We have undertaken an iterative process to design and test a patch that will replace infarcted tissue and induce myocardial regeneration to improve heart function. The result is a composite scaffold design composed of an endocardial patch to provide mechanical stability and an injectable filler material to provide a regenerative scaffold environment. This project provides a vital first step toward a final solution for myocardial regeneration.
Files	CardiacScaffoldMQPReport.pdf