Title page for E-project-033008-212524

Project Type MQP

Submission date 2008-03-30

Authors
Christine I Cronin, CM
Andrea L Kadilak, CM

URN E-project-033008-212524

Title Utilizing the Quartz Crystal Microbalance with Dissipation to Bind Cecropin P1 to Escherichia coli

Advisor
Camesano, Terri Anne, CM

Availability unrestricted

Abstract
The goal of this project was to study the binding and deactivation potential of the AMP cecropin P1 with eleven strains of E. coli with varying LPS membrane structures, using the quartz crystal microblance with dissipation (QCM-D. Three strains of E. coli (O157:H7, O113:H4, and O35:K-:H10) showed preferential binding with cecropin P1 and resulted in a higher percentage of the bacteria dead when in the presence of the AMP.

Files
MQP.pdf

Browse by Author | Browse by Department | Search all available E-projects

Questions? Email project-questions@wpi.edu
Maintained by webmaster@wpi.edu

Project Type	MQP
Submission date	2008-03-30
Authors	Christine I Cronin, CM Andrea L Kadilak, CM
URN	E-project-033008-212524
Title	Utilizing the Quartz Crystal Microbalance with Dissipation to Bind Cecropin P1 to Escherichia coli
Advisor	Camesano, Terri Anne, CM
Availability	unrestricted
Abstract The goal of this project was to study the binding and deactivation potential of the AMP cecropin P1 with eleven strains of E. coli with varying LPS membrane structures, using the quartz crystal microblance with dissipation (QCM-D. Three strains of E. coli (O157:H7, O113:H4, and O35:K-:H10) showed preferential binding with cecropin P1 and resulted in a higher percentage of the bacteria dead when in the presence of the AMP.
Files	MQP.pdf