Title page for E-project-042108-132930

Project Type	MQP
Submission date	2008-04-21
Authors	Michael Fakharzadeh, BE Greg A Fredette, BE Emily P Martin, BE
URN	E-project-042108-132930
Title	A Clinically Applicable Scaffold for Cardiac Regeneration
Advisor	Gaudette, Glenn R, BE
Availability	unrestricted
Abstract Myocardial infarction occurs when oxygen is depleted from cardiac muscle. Post myocardial infarction, the left ventricular wall is weakened due to the formation of scar tissue. As a result, a ventricular aneurysm may occur. This project aims to find a method of reinforcing the weakened tissue and restoring normal cardiovascular function. A scaffold for cardiac regeneration will provide the long term reinforcement necessary to prevent ventricular aneurysms and restore normal heart function. This paper proposes a method of restoring cardiac tissue through the use of a novel implantation method using an hMSC seeded scaffold that will temporarily support the area of weakened tissue and aid in the production of cardiac myocytes to re-establish a healthy ventricular wall.
Files	MQPClinicallyApplicableScaffold.pdf

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