
Project Type MQP Submission date 2008-04-21 Authors Teresse M deRham, BIO Katelyn A Leblanc, BIO Min Zhang, BC URN E-project-042108-201623 Title Isolation and Characterization of New Mutations in the mig-10 gene of Caenorhabditis elegans Advisors Buckholt, Michael Allan, BB Rulfs, Jill, BC Ryder, Elizabeth F, BIO Availability unrestricted Abstract
During development in Caenorhabditis elegans (C.elegans), several neurons migrate to specific locations, within the body; this is important in the formation of the nervous system. Mutations in the mig-10 gene have been phenotypically identified by incomplete migration of those cells and the truncation of the excretory cell. This project focuses on identification of additional mutations in the gene, isolated by non-complementation screening, and characterized using PCR and restriction digestion. Missense mutations may identify functional domains in the MIG-10 protein.
Files Mig-10MQPFinalDraft4-23-08.pdf
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