Worcester Polytechnic Institute Electronic Projects Collection

Title page for E-project-042108-201623


Project TypeMQP
Submission date2008-04-21
Authors
  • Teresse M deRham, BIO
  • Katelyn A Leblanc, BIO
  • Min Zhang, BC
  • URNE-project-042108-201623
    TitleIsolation and Characterization of New Mutations in the mig-10 gene of Caenorhabditis elegans
    Advisors
  • Buckholt, Michael Allan, BB
  • Rulfs, Jill, BC
  • Ryder, Elizabeth F, BIO
  • Availability unrestricted

    Abstract

    During development in Caenorhabditis elegans (C.elegans), several neurons migrate to specific locations, within the body; this is important in the formation of the nervous system. Mutations in the mig-10 gene have been phenotypically identified by incomplete migration of those cells and the truncation of the excretory cell. This project focuses on identification of additional mutations in the gene, isolated by non-complementation screening, and characterized using PCR and restriction digestion. Missense mutations may identify functional domains in the MIG-10 protein.

    Files
  • Mig-10MQPFinalDraft4-23-08.pdf

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