Title page for E-project-042407-183639

Project Type MQP

Submission date 2007-04-24

Author
Belinda Barbagallo, BIO

URN E-project-042407-183639

Sponsor UMASS Medical School

Title Stem Cell Survey of Human Sebaceous Tumors

Advisor
Adams, David S., BB

Availability unrestricted

Abstract
Mutations in stem cell signaling caused by alterations in the Lef1 beta-catenin pathway can lead to the development of sebaceous tumors in humans. A survey of known stem cell markers was conducted on a human sebaceous tumor line and on normal skin using immunoflourescence, PCR and Western Blots to verify the existence of stem cells in sebaceous tumors. The resulting data supports the existence of cancer stem cells in sebaceous tumors.

Files
MQP.pdf

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Project Type	MQP
Submission date	2007-04-24
Author	Belinda Barbagallo, BIO
URN	E-project-042407-183639
Sponsor	UMASS Medical School
Title	Stem Cell Survey of Human Sebaceous Tumors
Advisor	Adams, David S., BB
Availability	unrestricted
Abstract Mutations in stem cell signaling caused by alterations in the Lef1 beta-catenin pathway can lead to the development of sebaceous tumors in humans. A survey of known stem cell markers was conducted on a human sebaceous tumor line and on normal skin using immunoflourescence, PCR and Western Blots to verify the existence of stem cells in sebaceous tumors. The resulting data supports the existence of cancer stem cells in sebaceous tumors.
Files	MQP.pdf