Worcester Polytechnic Institute Electronic Projects Collection

Title page for E-project-042408-112010


Project TypeMQP
Submission date2008-04-24
Authors
  • Endri Angjeli, BE
  • Amid Dolatshahi Zand, BE
  • URNE-project-042408-112010
    TitlefMRI Analysis of Brain Refractory Period Activity in Nicotine-Addicted Rat Models
    Advisor
  • Sullivan, John M, ME
  • Availability unrestricted

    Abstract

    The objective of this study was to use functional Magnetic Resonance Imaging to investigate the brain activity of nicotine-addicted rats when the stimulus was introduced during the refractory period. The results confirmed that regions of the brain normally activated by nicotine are relatively inactive during the refractory period. These results coupled with other studies of drug reaction can be used in the development of pharmaceuticals aimed at specific regions of the brain or at determining targeted drug delivery schedules.

    Files
  • MQP_REPORT_Zand_Angjeli.pdf

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