Worcester Polytechnic Institute Electronic Projects Collection

Title page for E-project-042408-114444

Project TypeMQP
Submission date2008-04-24
Authors
  • Todd Christopher Bitner, BE
  • Lindsay Deitelbaum, BE
  • Timothy David Ebner, BE
  • Hristina Srbinoska, BE
    • URNE-project-042408-114444
    TitleDesign of a Biaxial Device for Measuring Cell Contractile Forces
    Advisors
  • Billiar, Kristen, BE
  • Rolle, Marsha W, BE
    • Availability unrestricted

    Abstract

    Determining the contractile forces present in three dimensional model systems of wound healing will further our understanding of how healthy tissue repair and remodeling differs from conditions such as hypertrophic scarring, chronic ulcers, and edema. Previous researchers have quantified both the active cellular contractile forces and matrix contribution to tissue contraction under uniaxial loading. A new model is needed to determine forces as they occur naturally in tissue that is loaded multiaxially. In this paper we present the design of a computer controlled biaxial contractile force culture monitor.

    Files
  • MQP_KLB0702_Design_of_a_Biaxial_Device_for_Measuring_Cell_Contractile_Forces.pdf

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