Project Type MQP Submission date 2012-04-25 Author Erin Lynn Armstrong, BIO URN E-project-042512-135727 Title Characterization of the Interaction Between Myosin XIa and RabA4 in Physcomitrella patens Advisor Vidali, Luis, BB Availability restricted
In the moss Physcomitrella patens, myosin XI mediated polarized tip growth is essential for growth and expansion. It has been hypothesized that, during polarized growth, secretory vesicles move to the tip of the expanding cell via an interaction between the myosin XI globular tail and RabA4. In this study, we show that several mutations in the putative binding region for RabA4 on the myosin XI tail produce the same phenotype as a myosin XIa knockdown, suggesting an interaction with RabA4.
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