Title page for E-project-042512-135727

Project Type MQP

Submission date 2012-04-25

Author
Erin Lynn Armstrong, BIO

URN E-project-042512-135727

Title Characterization of the Interaction Between Myosin XIa and RabA4 in Physcomitrella patens

Advisor
Vidali, Luis, BB

Availability restricted

Abstract
In the moss Physcomitrella patens, myosin XI mediated polarized tip growth is essential for growth and expansion. It has been hypothesized that, during polarized growth, secretory vesicles move to the tip of the expanding cell via an interaction between the myosin XI globular tail and RabA4. In this study, we show that several mutations in the putative binding region for RabA4 on the myosin XI tail produce the same phenotype as a myosin XIa knockdown, suggesting an interaction with RabA4.

Files
Armstrong_MQP_Final.pdf
indicates that a file or directory is accessible from the WPI campus network only.

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Project Type	MQP
Submission date	2012-04-25
Author	Erin Lynn Armstrong, BIO
URN	E-project-042512-135727
Title	Characterization of the Interaction Between Myosin XIa and RabA4 in Physcomitrella patens
Advisor	Vidali, Luis, BB
Availability	restricted
Abstract In the moss Physcomitrella patens, myosin XI mediated polarized tip growth is essential for growth and expansion. It has been hypothesized that, during polarized growth, secretory vesicles move to the tip of the expanding cell via an interaction between the myosin XI globular tail and RabA4. In this study, we show that several mutations in the putative binding region for RabA4 on the myosin XI tail produce the same phenotype as a myosin XIa knockdown, suggesting an interaction with RabA4.
Files	Armstrong_MQP_Final.pdf indicates that a file or directory is accessible from the WPI campus network only.