Project Type MQP Submission date 2006-04-27 Author Jaclyn Ann Therrien, BC URN E-project-042706-125539 Sponsor University of Massachusetts Medical School Title Histone and Runx2 Gene Expression During Embryoid Body Differentiation of Human Embryonic Stem Cells Advisor Ryder, Elizabeth F, BB Availability unrestricted Abstract
Human embryonic stem cells can be induced to form embryoid bodies which contain all three germ layers of the human body. Histone expression is tightly coupled to cell growth while Runx2 is essential for bone differentiation. This project tested the hypothesis that when stem cells cease to proliferate and differentiate into embryoid bodies, the Runx2 gene is induced.
Files FinalMQP.pdf
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