Project Type MQP Submission date 2005-04-28 Author William Edward Salomon, BIO URN E-project-042805-143027 Title Investigation of HIV-1 Variants with Broader Tropism than Wild-type Virus Advisor Adams, David S., BB Availability unrestricted Abstract
HIV-1 uses specific cell surface receptors to gain entry into host cells. Different strains vary in ability to infect cells with low receptor concentrations. The MQP's purpose was to analyze molecular clones of an HIV variant that had broad tropism for immune cells. These clones were tested for their ability to fuse with cells expressing known receptor concentrations. The data shows that this HIV variant was more fusiogenic for cells with low receptor expression than the wild type strain.
Files MQP_Report_Final.pdf
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