Worcester Polytechnic Institute Electronic Projects Collection

Title page for E-project-043009-134220

Project TypeMQP
Submission date2009-04-30
Authors
  • Kathryn Anne Bomba, BB
  • Eva Zipkin, BB
    • URNE-project-043009-134220
    SponsorUMass Medical School
    TitleCharacterization of Cancer Stem Cells in Tumor Pathogenesis
    Advisor
  • Adams, David S., BB
    • Availability unrestricted

    Abstract

    Recent studies have shown that many cancerous tumors contain "cancer stem cells" (CSCs) that may be responsible for the self-renewing properties of the tumor. A common cancer treatment, chemotherapy, targets rapidly dividing cells, but could possibly be ignoring the more slowly dividing CSCs. The CSCs were characterized in a variety of tumors using immunofluorescence to identify stem cell markers after treatment with a common chemotherapy, Doxorubicin. The resulting data show statistically significant evidence for the presence of stem cell markers in cells left behind after chemotherapy treatment.

    Files
  • MQP.pdf

    There is one file which has been withheld at the advisor's request.

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