Worcester Polytechnic Institute Electronic Projects Collection

Title page for E-project-043009-143657


Project TypeMQP
Submission date2009-04-30
Author
  • Richard Paul Pampuro, CM
  • URNE-project-043009-143657
    TitlePhotoresist Derived Carbon as a Substratum For Neuron Cell Culture
    Advisor
  • Zhou, Hong Susan, CM
  • Availability unrestricted

    Abstract

    Photoresist derived carbon films offer a unique set of properties that may prove useful as substratum for neuron cell growth. At this early stage in realizing the material's potential as a platform for neuron culture, it is necessary to examine surface properties and neuronal cell behavior. Surfaces are characterized by means relevant for studying cell-surface response, including electrochemistry and surface energy. Comparing gene expression levels, adhesion and morphology of PC12 cells grown on photoresist derived carbon to that of alternative materials elucidates cell-surface interactions in context of known surface characteristics. Results show that photoresist derived carbon is a viable alternative to current materials, offering the advantages of modification and electrical properties.

    Files
  • rpampuroMQPfinal.pdf

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