Title page for E-project-050109-162917

Project Type MQP

Submission date 2009-05-01

Author
Kyle Feeley, BIO

URN E-project-050109-162917

Title Isolation of Viral Isolates With Altered Growth Properties and Virulence

Advisor
Adams, David S., BB

Availability unrestricted

Abstract
The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and to determine the best candidate for a new progenitor stock. This determination was made through plaque assays for the in vitro study, and through ICCS FACS analysis for the in vivo study. The results indicate that the #11 72h Pichinde isolate was the best candidate because it grew consistently to a high titer in vitro and produced the most pronounced immune response in vivo.

Files
Kyle_Feeley_MQP_Final.pdf

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Project Type	MQP
Submission date	2009-05-01
Author	Kyle Feeley, BIO
URN	E-project-050109-162917
Title	Isolation of Viral Isolates With Altered Growth Properties and Virulence
Advisor	Adams, David S., BB
Availability	unrestricted
Abstract The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and to determine the best candidate for a new progenitor stock. This determination was made through plaque assays for the in vitro study, and through ICCS FACS analysis for the in vivo study. The results indicate that the #11 72h Pichinde isolate was the best candidate because it grew consistently to a high titer in vitro and produced the most pronounced immune response in vivo.
Files	Kyle_Feeley_MQP_Final.pdf