Title page for ETD etd-0430101-122300

Document Type thesis

Author Name Garramone, Samantha

URN etd-0430101-122300

Title Structure-Property Relationships in Angioplasty Balloons

Degree MS

Department Materials Science & Engineering

Advisors
Satya S. Shivkumar, Advisor
Richard D. Sisson, Jr., Department Head

Keywords
angioplasty balloon
multilayer
polymer

Date of Presentation/Defense 2001-04-26

Availability unrestricted

Abstract
Balloon angioplasty, used to clear clogged blood vessels, is the most common medical intervention in the world. In an effort to improve on an angioplasty balloon currently on the market, extruded tubes were designed that were comprised of different numbers of layers of an 80/20 ratio of polyethylene terephthalate (PET) to a thermoplastic elastomer. Balloons were fabricated from these tubes, and tested for burst strength, puncture resistance, and compliance. Lastly, these properties were correlated to the material configuration of the balloons. It was found that, although the burst strength and compliance of the balloons was not significantly effected, increasing the number of layers while keeping the ratio of materials constant lead to a linear increase in the puncture resistance and toughness of the balloons. This is important because it shows that one of the angioplasty balloons currently sold can be improved simply by changing the configuration of the materials, instead of having to research new medical grade polymers and how to process them.

Files
garramone.pdf

Browse by Author | Browse by Department | Search all available ETDs

Questions? Email etd-questions@wpi.edu
Maintained by webmaster@wpi.edu

Document Type	thesis
Author Name	Garramone, Samantha
URN	etd-0430101-122300
Title	Structure-Property Relationships in Angioplasty Balloons
Degree	MS
Department	Materials Science & Engineering
Advisors	Satya S. Shivkumar, Advisor Richard D. Sisson, Jr., Department Head
Keywords	angioplasty balloon multilayer polymer
Date of Presentation/Defense	2001-04-26
Availability	unrestricted
Abstract Balloon angioplasty, used to clear clogged blood vessels, is the most common medical intervention in the world. In an effort to improve on an angioplasty balloon currently on the market, extruded tubes were designed that were comprised of different numbers of layers of an 80/20 ratio of polyethylene terephthalate (PET) to a thermoplastic elastomer. Balloons were fabricated from these tubes, and tested for burst strength, puncture resistance, and compliance. Lastly, these properties were correlated to the material configuration of the balloons. It was found that, although the burst strength and compliance of the balloons was not significantly effected, increasing the number of layers while keeping the ratio of materials constant lead to a linear increase in the puncture resistance and toughness of the balloons. This is important because it shows that one of the angioplasty balloons currently sold can be improved simply by changing the configuration of the materials, instead of having to research new medical grade polymers and how to process them.
Files	garramone.pdf