Worcester Polytechnic Institute Electronic Theses and Dissertations Collection

Title page for ETD etd-050114-143014


Document Typethesis
Author NamePeters, Jeffrey
URNetd-050114-143014
TitleFormation of Vesicles in Lipid-Liquid Crystal Colloidal Mixtures
DegreeMS
DepartmentPhysics
Advisors
  • Germano Iannacchione, Advisor
  • Izabela Stroe, Committee Member
  • Keywords
  • calorimetry
  • vesicles
  • 5CB
  • liquid crystal
  • lipid
  • Date of Presentation/Defense2014-05-01
    Availability unrestricted

    Abstract

    The formation, phase ordering, and evolution has been studied in lipid and liquid crystal (LC) colloidal aqueous mixtures as a function of LC concentration and thermal history. The lipid used was 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine (POPC) while the liquid crystal was pentylcyanobiphenyl (5CB). POPC is a naturally occurring lipid in eukaryotic cell membranes and mimics many of the properties of human cell walls. 5CB is a polar liquid crystal that exhibits a thermodynamically stable orientationally

    ordered (nematic) state at room temperature. Colloidal dispersions were made at various 5CB and POPC concentrations in water and studied via optical microscopy (phase contrast, confocal, florescence, and cross-polarizing) to probe phase order and evolution as well as by calorimetry to study phase transformations. Very large vesicles (larger than 100 micrometers) were observed to form that appear to use the phase separated 5CB droplets as scaffolds. Also, there appears a unique promotion of dye (used to image the lipid bilayers) crystallization within liquid crystal domains well above room temperature.

    Files
  • Thesis_JP_GSI_2014.pdf

  • Browse by Author | Browse by Department | Search all available ETDs

    [WPI] [Library] [Home] [Top]

    Questions? Email etd-questions@wpi.edu
    Maintained by webmaster@wpi.edu