Life Sciences & Bioengineering Center
- Department Head
- Professor & Department Head, Chemistry & Biochemistry
- John C. Metzger Chemistry & Biochemistry
I received my undergraduate and graduate education at the University of Hamburg (Germany). My doctoral thesis was concerned with the development of infrared reflection-absorption spectroscopy for monolayers at the air/water interface. I came to the United States in 1994 as a postdoctoral student to join the research group of Professor Richard Mendelsohn at Rutgers University. During that time I conducted biomedical research directed at the biophysical characterization of lung surfactant proteins, bone tissue, and lipid/protein interactions.
In 1997 I returned to Germany and became a habilitation candidate at the Max Planck Group for liquid crystal research at the University of Halle. During this time, I initiated my independent research career, which is aimed at the biophysical characterization of lipid-mediated protein functions as well as the development of vibrational spectroscopic imaging for the characterization of human tissue. Before joining WPI in 2011, I spent 11 years at Kent State University as assistant and later associate professor and graduate program coordinator. My research is funded through grants from the National Institutes of Health and the National Science Foundation. I strongly believe in the integration of research and teaching, and throughout my career I have secured several grants aimed at providing undergraduate students with enhanced educational and research experiences.
WPI offers an exceptional environment for inquiry and project-based learning, which is in my opinion the best and most inspiring way of teaching science. Science is taught at WPI in a societal context, which was for me an important aspect in deciding to join WPI.
- Lipid/protein interactions
- Signal transduction at biological membranes
- Bone tissue research
- Vibrational spectroscopic imaging
- Dipl. Chem., University of Hamburg, 1988
- Dr. rer. nat., University of Hamburg, 1994
- R.E Redfern, M.-C. Daou, L. Li, M. Munson, A. Gericke, and A. Ross (2010). “A Mutant Form of PTEN Linked to Autism,” Protein Sci. 19: 1948–1956.
- E.E. Kooijman, M. Gangoda, and A. Gericke (2009). “Ionization Properties of Phosphatidylinositolpolyphosphates in Mixed-Model Membranes,” Biochemistry 48: 9360 - 9371.
- A. Ross and A. Gericke (2009). “Phosphorylation Keeps PTEN Phosphatase Closed for Business,” Proc. Natl. Acad. Sci. 106: 1297 – 1298.
- R.E. Redfern, D.A. Redfern, M.L. Furgason, M. Munson, A.H. Ross, and A. Gericke (2008). “Phosphoinositides Selectively Bind to PTEN Phosphatase and Induce Structural Changes,” Biochemistry, 47: 2162 – 2171.
- A. Gericke, C. Qin, L. Spevak, Y. Fujimoto, W.T. Butler, E. Sorensen, and A.L. Boskey (2005). “Importance of Phosphorylation for Osteopontin Regulation of Biomineralization,” Calcified Tissue International 77: 45 -54.
Spotlight On: Current Research
A major aspect of our research is biophysical characterization of phosphoinositide-mediated protein functions. Phosphoinositides have been shown to control a broad range of physiological functions by attracting proteins to specific cellular sites.
- Postdoctoral Fellowship (DFG)
- Habilitation Fellowship (DFG)