Life Sciences & Bioengineering Center, 4008
Ki H. Chon
- Professor & Department Head, Biomedical Engineering
- Affiliated with:
Research in my laboratory involves medical instrumentation, biosignal processing, modeling, simulation and development of novel algorithms to understand dynamic processes and extract distinct features of physiological systems. Currently, there are five ongoing research projects in my laboratory:
Evaluation of the effects of oxygen toxicity and hyperbaric environments on the autonomic nervous system: The goal is to develop noninvasive approaches for early detection of and differentiation between fatal and nonfatal decompression sickness (DCS). Both swine- and human experiments are being conducted to test the robustness of our algorithm for early detection and prediction of DCS.
Real-time detection of atrial fibrillation, atrial flutter, and atrial tachycardia from surface ECG: The goal is to develop real-time algorithms for accurate detection of atrial fibrillation, flutter, and tachycardia that are especially applicable for Holter monitoring devices.
Spatio-temporal analysis of renal autoregulation: The goal is to understand how nephrons synchronize to autoregulate renal blood flow using laser speckle imaging techniques.
Noninvasive assessment of diabetic cardiovascular autonomic neuropathy (DCAN) from surface ECG or pulse oximeter: The goal is to develop noninvasive approaches for early detection of DCAN. Diabetic and control mice are used to collect ECG data and validation of computational data analysis results is measured against Western blot and immunohistochemistry.
Vital sign monitoring from optical recordings with a mobile phone: The goal is to utilize a mobile phone video camera to extract vital sign and physiological parameters, which may include heart rate, oxygen saturation, respiratory rate, atrial fibrillation detection, blood loss detection, and the dynamics of the autonomic nervous system.
- BS University of Connecticut
- MS University of Iowa
- MS University of Southern California
- PhD University of Southern California
- Selvaraj, N., K.H. Shelley, D.G. Silverman, N. Stachenfeld, N. Galante, J.P. Florian, Y. Mendelson, and K.H. Chon, A novel approach using time-frequency analysis of pulse oximeter data to detect progressive hypovolemia induced with lower body negative pressure in spontaneously breathing healthy subjects. IEEE Trans. BME, In Press.
- Lee, J and K.H. Chon Time-Varying Autoregressive Model-Based Multiple Model Particle Filtering Algorithm for Respiratory Rate Extraction from Pulse Oximeter IEEE Trans. BME, 58:790-794, 2011.
- Bai, Y., R. Mahon, J. White, P. Brink, and K.H. Chon, Impariment of autonomic nervous function during decompression sickness in swine.. J. Appl. Physiol., 106:1004-1009, 2009.
- Siu, K.L. and K.H. Chon, On the efficacy of the combined use of the cross-bicoherence with surrogate data technique to statistically quantify the presence of nonlinear interactions, Annals of BME, 37:1839-1848, 2009.
- Dash, S., K.H. Chon, S. Lu, and E. Raeder, Automatic real-time detection of atrial fibrillation. Annals of BME, 37:1701-1709, 2009.