BME Seminar: “Diffuse Optical Imaging for Diagnosis and Treatment of Brain Diseases” by Fenghua Tian, PhD, BME Faculty Candidate in Neuroengineering

Thursday, March 21, 2019
12:00 pm to 1:00 pm
Floor/Room #: 
Fenghua Tian, PhD
Department of Biomedical Engineering
University of Texas at Arlington
Research Assistant Professor


Abstract:   Diffuse optical imaging (DOI), also referred to as functional near-infrared spectroscopy (fNIRS), is an emerging technology that has received increasing attention in recent years because it is safe, portable and relatively low-cost. It uses near-infrared light between 650-900 nm to penetrate the tissues. The light is primarily absorbed by oxygenated and deoxygenated hemoglobin, and cytochrome c oxidase. Therefore, it is sensitive to the changes in cerebral hemodynamics and metabolism. This technology has now reached a tipping point where users are exploring its potential for a wide range of health science and clinical applications. The NeuroPhotonics Lab (NPL) at the University of Texas at Arlington has been dedicated to methodological development in this field towards better image quality and more robust signal detection. Most recently, we have combined DOI with low-level transcranial laser stimulation (TLS) for optimized and personalized therapy. This noninvasive, imaging-guided neuromodulation has great therapeutic potentials for various neurological diseases such as posttraumatic stress disorder (PTSD), major depression, traumatic brain injury (TBI), and neurodegenerative diseases.

Biography: Dr. Fenghua Tian received his B.S. and Ph.D. degrees in biomedical engineering from the Tsinghua University, Beijing, China. Currently he is a research assistant professor at the Department of Bioengineering, the University of Texas at Arlington. He has over ten years of research experience in biomedical optics with focus on brain imaging and cerebrovascular functions. His research interests include: 1) optical neuroimaging towards whole-head coverage, accurate localization and robust signal detection; 2) noninvasive neuromodulation for a broad spectrum of neurological diseases; and 3) multimodal assessment of brain injuries for critically ill patients. The technologies used his research include DOI/fNIRS, diffuse correlation spectroscopy (DCS), electroencephalography (EEG), repetitive transcranial magnetic stimulation (rTMS), transcranial laser stimulation (TLS), and so on. Dr. Tian has served as principal investigator (PI) on several research projects funded by National Institutes of Health (NIH) and American Heart Association (AHA). He is the author of more than 45 peer-reviewed publications, and a scientific reviewer for more than 20 journals and conferences. He is a senior member of SPIE – the International Society for Optics and Photonics, a member of American Society for Laser Medicine & Surgery (ASLMS), and a member of American Heart Association (AHA).
Department of Biomedical Engineering
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