CANCELED - Chemistry and Biochemistry Seminar - David Nagib, The Ohio State University | C-H and C-O Functionalization via Radical Chaperones

Wednesday, October 23, 2019
12:00 pm
Floor/Room #: 
GP 1002

C-H and C-O Functionalization via Radical Chaperones


David Nagib
Assistant Professor
Department of Chemistry and Biochemistry
The Ohio State University

Host: Patricia Musacchio, Ph.D.


Our research is focused on harnessing the untapped reactivity of abundant chemical feedstocks to enable late-stage functionalization of medicinally relevant molecules. We have recently developed new approaches for selective C-H and C-O functionalization of alcohols, amines, and carbonyls, using a combination of radical (1e-) and closed shell (2e-) processes that act in concert with one another. These radical chaperone strategies have enabled discovery of new classes of reactivity to streamline the synthesis of complex molecules with biological and industrial significance.