Downstream Principles and Techniques - WPI Biomanufacturing Education and Training Center

Tuesday, May 12, 2020 to Friday, May 15, 2020
8:00 am to 4:00 pm
Biomanufacturing Education & Training Center
50 Prescott Street
Worcester, MA 01609
United States
Floor/Room #: 
Biomanufacturing Education and Training Center

Improve your basic skills in separation and purification of bio-manufactured products with both single-use and stainless equipment. This hands-on training includes theoretical background information on cell harvest and clarification, TFF, and chromatography, including column packing. You will also develop a better understanding of the various protein characteristics and how they affect the purification process, how resins are selected, and how a purification process is developed.

Class size is limited to 18 – reserve your seat early!


  • Understand the principles of centrifugation and how cell harvesting and clarification is completed
  • Understand the principles and applications for depth filtration
  • Understand how protein characteristics facilitate the purification process
  • Become familiar with the different types of chromatographic processes and the principles behind each type
  • Identify the components of a chromatography system and their functions
  • Perform column packing and peak evaluation
  • Identify the components of a TFF system and their functions
  • Understand how viruses are inactivated and removed
  • Understand how a purification process is developed


  • Program Start:  May 12-15, 2020  |  November 10-13, 2020
  • Registration Deadline: Two weeks prior to program start
  • Time: 8:00 a.m. to 4:00 p.m.
  • Location: Biomanufacturing Education & Training Center (BETC)
    WPI Gateway Park 2, 50 Prescott St (2nd floor), Worcester MA
  • Price: $3,900
  • CEU: 2.8

There are no academic prerequisites for this program

Who Should Attend

  • Biomanufacturing associates and operators involved in downstream operations
  • Biomanufacturing associates and operators involved in upstream processing who want to become cross-trained in purification
  • Biomanufacturing facility maintenance, metrology and engineering personnel responsible for purification areas
  • Project and program managers in the biomanufacturing industry
  • Sales and marketing personnel for equipment and material manufacturers that serve the biotechnology industry
  • Quality assurance personnel responsible for the review of downstream process documentation
  • Technical writers responsible for generating batch records and recipes
  • Process development associates
  • Research scientists
  • Bioprocess engineers
Phone Number: