WPI and UMass Lowell Award Seed Grants to Interdisciplinary Research Teams

I have a passion for understanding how living systems work, as well as for sharing my love of biology and research with the next generation of scientists and informed citizens.

The central goal of my lab is to understand the regulatory mechanisms that underlie mycobacterial stress tolerance. We combine genetics, genomics, transcriptomics and biochemistry to understand how mycobacteria respond to, and ultimately survive, stressful conditions.

I am an Assistant Professor of Anthropology and Rhetoric. Before joining WPI, I was a postdoctoral fellow at the University of California, Berkeley. My work is animated by an intellectual curiosity with how ideas travel across time and space, and generate diverse practices of acting, seeing, and being in the world. I am especially intrigued by situations in which people come to ask new questions about themselves and others, in ways that require reconsideration of past experiences and imagining of future possibilities.

Jennifer deWinter has long been interested in how culture (which is local) moves internationally. She has spent a number of years analyzing anime, comics, and computer games as part of global media flows in order to understand how concepts such as "art," "culture," and "entertainment" are negotiated. In 2003, Professor deWinter joined the Learning Games Initiative, a group of scholars and game designers dedicated to the general study of games and the use of games to teach concepts and skills in particular.

I use physical principles at the molecular scale to solve macroscopic problems in biology, e.g. How do a molecule's mechanical properties influence the behavior of a cell?  How do single molecule measurements relate to muscle function?  To answer such questions, I use a combination of computer simulations and mathematical analysis.  This theoretical work is complemented by experiments performed by my collaborators.  In my teaching, I enjoy emphasizing connections between math and other disciplines.

My research is in the broad, interdisciplinary field of synthetic biology, which applies engineering principles to biology. Within this field, we apply chemical engineering tenets to reprogram the DNA of yeasts, bacteria, and fungi so their metabolism produces interesting molecules. By treating these cells as "chemical factories," we can approach and solve problems in biofuels, biomaterials, and biosensors from a chemical engineer's point of view.

The Musacchio research group is interested in utilizing radical intermediates to find common ground between organic chemistry and chemical biology. Specifically, we are interested in developing radical-mediated methodologies for complex molecule synthesis, identifying new bioconjugation strategies, and establishing radical-mediate biocatalysis systems.