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DTSTART;TZID=America/New_York:20260612T110000
DTEND;TZID=America/New_York:20260612T115000
URL;TYPE=URI:https://www.wpi.edu/news/calendar/events/department-mathematic
 al-sciences-applied-math-lecture-yuehui-xu-wpi
SUMMARY:Department of Mathematical Sciences Applied Math Lecture: Yuehui Xu
 , WPI
DESCRIPTION:\n\n\n      \n      \n\n\n\nFriday, June 12th, 2026\n11:00am – 
 11:50am\nHiggins Labs 114\n\nSpeaker:Yuehui Xu, WPI\nTitle:A Mathematical 
 Framework for Biomechanics in a 3D Cell Migrating on a Flat Substrate\nAbs
 tract: Cell migration is essential in wound healing, immune response, and 
 cancer metastasis. This work presents a 3D computational model of migratin
 g cells that incorporates viscoelastic mechanics, protrusion, focal adhesi
 on dynamics, and intracellular interactions. Simulations reproduce realist
 ic migration behavior and force patterns, while sensitivity analyses ident
 ify key mechanical drivers. The framework is extended to include nuclear m
 echanics under confinement, providing insight into deformation and force g
 eneration during confined migration.\n
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