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DTSTAMP:20260916T150638Z
DTSTART;TZID=America/New_York:20260928T120000
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URL;TYPE=URI:https://www.wpi.edu/news/calendar/events/bme-seminar-jon-grasm
 an-njit-generating-aligned-tissues-enhance-skeletal-muscle-regeneration
SUMMARY:BME Seminar: Jon Grasman\, NJIT: "Generating Aligned Tissues to Enh
 ance Skeletal  Muscle Regeneration”
LOCATION:United States
DESCRIPTION:Seminar Series\n“Generating Aligned Tissues to Enhance Skelet
 al Muscle Regeneration”\n\n\n\n      \n      \n\n\n\nJonathan Grasman\, 
 PhD\nNJIT\nBiomedical Engineering\nAbstract: A significant limitation in t
 he fabrication of tissue mimetics for skeletal muscle tissue engineering i
 s that constructs often result in misaligned myofiber growth\, which imped
 es efficient force production and ultimately limits functional regeneratio
 n. Our goal is to rationally design biomaterial environments that recapitu
 late myogenic niches to promote aligned muscle growth and enhance wound he
 aling. In this talk\, we will discuss ongoing strategies in the Grasman la
 b to develop mimetics for the study of muscle growth. First\, we will desc
 ribe efforts to incorporate insulin-like growth factor 1 (IGF1) into aniso
 tropic scaffolds using chaperone proteins as an acellular\, off-the-shelf 
 product to enhance muscle regeneration after traumatic injury. We will tra
 nsition to cellular constructs\, where we carefully manipulate material co
 mposition and boundary conditions to promote myofiber alignment in a platf
 orm where we can simultaneously quantify construct contractile properties.
 \nBio: Jonathan Grasman (he/him/his) is an Assistant Professor in the Depa
 rtment of Biomedical Engineering at the New Jersey Institute of Technology
  (NJIT)\, where he directs the Tissue Innervation and Muscle Mimetics lab.
  His research program focuses on regenerating skeletal muscle using both c
 ellular and acellular strategies\, as well as studying mechanisms of inner
 vation to achieve targeted axonal guidance. He received his B.S. in bioeng
 ineering from the University of Pittsburgh\, his Ph.D. in biomedical engin
 eering from Worcester Polytechnic Institute\, and he completed his postdoc
 toral training in tissue engineering at Tufts University. Dr. Grasman rece
 ived NRSA fellowships in support of both his pre- and postdoctoral studies
 \, and is currently funded by the NIH and the New Jersey Commission on Spi
 nal Cord Research. He has recently been honored as a member of the Nationa
 l Academy of Inventors\, and has received several teaching and mentoring a
 wards at NJIT.\nFor a zoom link please contact Kate Harrison at kharrison@
 wpi.edu
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