Title page for E-project-030207-112622

Project Type MQP

Submission date 2007-03-02

Authors
Melissa A. Byrne, BE
Benjamin C. Cleveland, BE
Joseph E. Marturano, BE

URN E-project-030207-112622

Title Design of a reproducible murine fracture device

Advisor
Billiar, Kristen, BE

Availability unrestricted

Abstract
Mouse models are commonly used to investigate bone healing and test new treatments. The objectives of this project were to design a fracture device to create a reproducible transverse fracture in the mouse femur and to establish the limits of achieving transverse fractures. Testing with 26.4 +/- 6.1g wildtype mice (n=120) developed a model equation of mv^2=0.292 to predict a 95% transverse fracture success rate. These results are useful to researchers who are interested in obtaining a higher transverse fracture success rate.

Files
MQP_KLB0602_Fracture_Device_2007.pdf

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Project Type	MQP
Submission date	2007-03-02
Authors	Melissa A. Byrne, BE Benjamin C. Cleveland, BE Joseph E. Marturano, BE
URN	E-project-030207-112622
Title	Design of a reproducible murine fracture device
Advisor	Billiar, Kristen, BE
Availability	unrestricted
Abstract Mouse models are commonly used to investigate bone healing and test new treatments. The objectives of this project were to design a fracture device to create a reproducible transverse fracture in the mouse femur and to establish the limits of achieving transverse fractures. Testing with 26.4 +/- 6.1g wildtype mice (n=120) developed a model equation of mv^2=0.292 to predict a 95% transverse fracture success rate. These results are useful to researchers who are interested in obtaining a higher transverse fracture success rate.
Files	MQP_KLB0602_Fracture_Device_2007.pdf