BME MS Thesis Defense: Chris Nguyen: “A Probabilistic Method to Model Progressive Metatarsal Fatigue Failure and Microdamage Accumulation”

Wednesday, July 2, 2025
8:30 a.m. to 9:30 a.m.

United States

Floor/Room #
1002
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WPI Biomedical Engineering with school seal

Master’s Thesis Defense 

Wednesday, July 2, 2025 

Gateway Park, Room GP 1002 

8:30am-9:30am 

“A Probabilistic Method to Model Progressive Metatarsal Fatigue Failure and Microdamage Accumulation” 

Chris Nguyen 

Abstract: To better understand the mechanisms of bone stress injuries (BSI) in metatarsals, we developed a program that modifies finite element (FE) models of metatarsals to mimic progressive fatigue damage through microdamage accumulation. Twenty-two human metatarsals were imaged using computed tomography (CT) and then cyclically loaded in uniaxial compression until failure. CT images were used to generate specimen-specific FE models, and a custom program was developed to iteratively simulate cyclic loading and microdamage accumulation associated with mechanical fatigue. Probability was incorporated into microdamage accumulation through a Weibull distribution. Fatigue life estimates were significantly affected by 1) the Weibull scatter variable, m, and 2) if damage occurred before or after yielding. Our findings show that the stiffness and displacement curves of the progressive damage model accurately represent those curves of the experimental data. This research is significant because it helps us better understand fatigue life and damage accumulation of bones in response to physical activity and contributes to prediction of BSI in humans. 

Thesis Advisor:  Defense Committee:   

Karen Troy, PhD 

Professor 

Biomedical Engineering 

Worcester Polytechnic Institute 

Zhenglun "Alan” Wei, PhD (Chair) 

Assistant Professor 

Biomedical Engineering 

Worcester Polytechnic Institute 

Songbai Ji, PhD 

Professor 

Biomedical Engineering 

Worcester Polytechnic Institute 

For a zoom link, please email kharrison@wpi.edu 

Audience(s)

Department(s):

Biomedical Engineering
Contact Person
Kate Harrison

Phone Number: