Toni worked at Brigham and Women's hospital in as a research associate in a respiratory epigenetics lab for 2 years before joining the Broad Institute in Cambridge, MA. There, she worked at the Genomics Platform as a technology development associate developing hybrid selection based sequencing methods and molecular barcoding strategies. She then moved to a research lab at the Broad, where she studied evolution in yeast as well as melanoma. During this time, she received her master's in biotechnology from Harvard University Extension School. She joined Professor Reeta Rao's lab as a full time PhD student at WPI in 2014.