Education:
Postdoc University of California, Berkeley 2019
PhD Princeton University 2017
BS The University of Texas at Austin 2012
The Musacchio research group is interested in utilizing radical intermediates to find common ground between organic chemistry and chemical biology. Specifically, we are interested in developing radical-mediated methodologies for complex molecule synthesis, identifying new bioconjugation strategies, and establishing radical-mediate biocatalysis systems.
Email
pzmusacchio@wpi.edu
Office Location
Office 3017 at 60 Prescott St
Research Interests
Research Interests:
Organic Synthesis; Electron Transfer Processes; Methodology Development; Protein Bioconjugation
Scholarly Work
A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation A. H. Christian, S. Jia, W. Cao, P. Zhang, A. T. Meza, M. S. Sigman, C. J. Chang, F. D. Toste, J. Am. Soc. 2019, 141, 0052. - 2019
A Radical Approach to the Copper Oxidative Addition Problem: Trifluoromethylation of Bromoarenes
C.C. Le, T. Q. Chen, T. Liang, P. Zhang, D. W. C. MacMillan, Science 2018, 360, 1010. - 2018
Metallaphotocatalysis: The Merger of Transition Photocatalysis and Transition Metal Catalysis (Review).
J.R. Twilton, C. C. Le, P. Zhang, M. H. Shaw, R. W. Evans, D. W. C. MacMillan, Nat. Rev. Chem. 2017, 1, 0052. - 2017
Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross
Electrophile Coupling
P. Zhang, C. C. Le, D. W. C. MacMillan, J. Am. Chem. Soc. 2016, 138, 8084. - 2016
Concise Approach to 1,4-Dioxygenated Xanthones via Novel Application of the Moore Rearrangement
A. L. Nichols, P. Zhang, S. F. Martin, Tetrahedron 2012, 68, 7591. - 2012
General and Expedient Synthesis of 1,4-Dioxygenated Xanthones
A. L. Nichols, P. Zhang, S. F. Martin, Org. Lett. 2011, 13, 4696. - 2011
Professional Highlights & Honors
Professional Highlights & Honors:
2019
American Cancer Society