Patricia Zhang headshot
Office 3017 at 60 Prescott St
Postdoc University of California, Berkeley 2019
PhD Princeton University 2017
BS The University of Texas at Austin 2012

The Musacchio research group is interested in utilizing radical intermediates to find common ground between organic chemistry and chemical biology. Specifically, we are interested in developing radical-mediated methodologies for complex molecule synthesis, identifying new bioconjugation strategies, and establishing radical-mediate biocatalysis systems.

Scholarly Work

A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation A. H. Christian, S. Jia, W. Cao, P. Zhang, A. T. Meza, M. S. Sigman, C. J. Chang, F. D. Toste, J. Am. Soc. 2019, 141, 0052. 2019

A Radical Approach to the Copper Oxidative Addition Problem: Trifluoromethylation of Bromoarenes
C.C. Le, T. Q. Chen, T. Liang, P. Zhang, D. W. C. MacMillan, Science 2018, 360, 1010. 2018

Metallaphotocatalysis: The Merger of Transition Photocatalysis and Transition Metal Catalysis (Review).
J.R. Twilton, C. C. Le, P. Zhang, M. H. Shaw, R. W. Evans, D. W. C. MacMillan, Nat. Rev. Chem. 2017, 1, 0052. 2017

Silyl Radical Activation of Alkyl Halides in Metallaphotoredox Catalysis: A Unique Pathway for Cross
Electrophile Coupling
P. Zhang, C. C. Le, D. W. C. MacMillan, J. Am. Chem. Soc. 2016, 138, 8084. 2016

General and Expedient Synthesis of 1,4-Dioxygenated Xanthones
A. L. Nichols, P. Zhang, S. F. Martin, Org. Lett. 2011, 13, 4696. 2011

Professional Highlights & Honors
, 2019
American Cancer Society