My research aims to develop a treatment for the millions of Americans suffering from myocardial infarction and other cardiovascular diseases. We are focused on regenerating mechanical and electrophysiological function in the heart. Our work has demonstrated the induction of adult cardiac myocytes into the cell cycle. We also have differentiated adult stem cells into cardiac myocytes. In addition, to confirm that the regenerated tissue is mechanically active, our lab has developed a method for accurately measuring regional function at very high spatial resolution in the heart.
Candidates in the Biomedical Engineering PhD program conduct ambitious self-directed research alongside some of the field’s best-known faculty. Whatever your interest, WPI’s extensive technical and scientific resources elevate your research possibilities.
- VitaThread protein-based sutures
- Phlebot, a robot for routine blood draws
- Development of immune modulating hydrogel that supports neural stem cell survival during an inflammatory response in an injured spinal cord lesion
- Building whole-organism neuropsychiatric disease models and high-throughput quantitative methods for identifying novel therapeutics using C. elegans
- An engineered microvascular network to enable an eventual cardiac tissue patch
- Creating a biomimetic composite scaffold that recapitulates the mechanical and functional properties of native heart muscle to promote regeneration