Email
fbrownewell@wpi.edu
Education
Postdoc Chemistry Stanford University
PhD Chemistry University of Vermont
I have enjoyed a blended career spanning research and development, heavy chemicals manufacturing, healthcare single use manufacturing, and academia. This experience has provided a unique interface between the theoretical and the practical. I understand the need for innovation and invention coupled with manufacturability. I bring this perspective to the classroom and the projects I engage.
I work closely with the Biomanufacturing Education and Training Center (BETC) with a strong focus on workforce development. I oversee programs and curricula aimed at individuals spanning entry-level manufacturing personnel through science and engineering staff working in the biomanufactuing sector. I am particularly interested in programs that create opportunity for the unemployed, under-employed, and non-technically employed to enter the stable, financially beneficial field of biomanufacturing. This sector is growing rapidly in the Worcester region and beyond. Efforts through the BETC not only provide desirable career opportunities for people in need of better employment, but also supports the broader industry in developing the skilled labor needed to continue growing and meeting the needs of their patient populations.
Research Interests
Biomimetic Structures
Modified Amino Acids
Modified Nucleic Acids
Non-bonded Interactions
Scholarly Work
DNA Bending at A Tracts Containing a Nonpolar Thymine Mimic, A. Maki, F.E. Brownewell, D. Liu, E.T. Kool, Nucleic Acids Research, 2002, 31(3), 1059.
The Phe-X-Glu DNA Binding Motif of MutS: The Role of Hydrogen Bonding in Mismatch Recognition, M.J. Schofield, F.E. Brownewell, S. Nayak, C. Du, E.T. Kool, P. Hsieh, J. Biol. Chem. 2001, 276(49), 45505.
Asymmetric Recognition of DNA Local Distortion: Structure-based Functional Studies of Eukaryotic msh2:msh6, K. Drotschmann, W. Yang, F.E. Brownewell, E.T. Kool, T.A. Kunkel, J. Biol. Chem. 2001, 276(49), 46225.
Stereoselective Alkylations of a Bicyclic Lactam Derived from Pyroglutamic Acid, R. Zhang, F.E. Brownewell, and J.S. Madalengoitia, Tetrahedron Lett. 1999, 40(14), 2707.
Pseudo-A(1, 3) Strain as a Key Conformational Control Element in the Design of Poly-L-proline Type II Peptide Mimics, R. Zhang, F.E. Brownewell, and J.S. Madalengoitia, J. Am. Chem. Soc. 1998, 120(16), 3894.
Professional Affiliations