Email
dkorkin@wpi.edu
Office
Fuller Labs, Room B22
Personal Website
Affiliated Department or Office
Bioinformatics & Computational Biology
Data Science
Biology & Biotechnology
Mathematical Sciences
Harold L. Jurist ’61 and Heather E. Jurist Dean’s Professor
Education
Postdoc Bioinformatics & Computational Biology University of California, San Francisco 2007
PhD Computer Science University of New Brunswick, Canada 2003
MS Applied Mathematics Moscow State University, Russia High Distinction 1999

My research is interdisciplinary and spans the fields of bioinformatics of complex diseases, computational genomics, systems biology, and biomedical data analytics. We bring expertise in machine learning, data mining, and massive data analytics to study molecular mechanisms underlying genetic disorders, such as cancer, diabetes, and autism, and deadly infections, such as pandemic flu. Our approaches benefit from integrating multi-omic, systems, and structural biology data. We also develop hardware-optimized algorithms to understand the evolution of animal and plant genomes on the large scale. Finally, we collaborate with experimental scientists to test biological hypotheses generated by computational predictions. Members of our lab have enjoyed working together on cutting-edge cross-disciplinary projects and participating in collaborations nationally and internationally.

Scholarly Work

The yeast protein interaction network has a capacity for self-organization
Literature Mining of Host-Pathogen Interactions: Comparing Feature-based Supervised Learning and Language-based Approaches
Fast protein binding site comparisons using visual words representation
A Soybean Cyst Nematode Resistance Gene Points to a New Mechanism of Plant Resistance to Pathogens
Mining host-pathogen interactions
Analyzing the Interaction of RseA and RseB, the Two Negative Regulators of the SigmaE Envelope Stress Response, Using a Combined Bioinformatic and Experimental Strategy

News

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Media Coverage

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Spectrum News 1
WPI professor's research could lead to new COVID-19 treatments

Spectrum News 1, Phys.org, and News-Medical.net covered the publication of a new paper by Dmitry Korkin, Harold L. Jurist ’61 and Heather E. Jurist Dean’s Professor of Computer Science, that reveals new details about the outer shell of the SARS-COV-2 virus particle.

Nautilus
The Enemy Made Visible

The science magazine Nautilus talked with Dmitry Korkin, Harold L. Jurist ’61 and Heather E. Jurist Dean’s Professor of computer science about his role in developing a “periodic table” of structural elements that make up the COVID-19 virus, and how it led a Scottish artist Angela Palmer to create a sculptural model of the virus first displayed at the Oxford Museum of Natural History.