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Bioinformatics & Computational Biology (BCB)

From sequencing the human genome to modeling living organisms, biology has gone digital, and WPI’s Bioinformatics & Computational Biology (BCB) program is at the forefront of this digital revolution.

Bioinformatics involves the collection, management, and analysis of biological data; Computational Biology is the development of quantitative models of biological systems. While many schools offer BCB as a concentration within a traditional Biology program, WPI’s program comprises three academic departments: Biology, Computer Science, and Mathematics.

Our program’s diverse environment encourages a collaborative mindset and access to a broad range of resources that promote creative solutions to pressing scientific questions. Undergraduate and graduate students work alongside expert faculty researchers to use cutting-edge, quantitative techniques to increase our understanding of biology and translate this knowledge into meaningful solutions.

Degrees & Certificates

Area of Study Bachelor Minor Certificate Master PhD
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Featuring Our Students

BS/MS Student, Class of 2021

Ann-Elizabeth Le is a BCB student that has done bioinformatics research in and outside of WPI. She is currently on track to complete her 5 year BS/MS for a bioinformatics degree. In her sophomore year, Ann had the opportunity to go to the Janelia Research Campus to present about a predicted protein function based on sequential overlaps from a novel bacteriophage through a two-part lab class and ISP. For the past three summers, she also worked at the Ragon Institute of MGH, MIT, and Harvard as an intern analyzing HIV antigen processing and presentation.

Ann-Elizabeth Le

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Photo of Ann-Elizabeth Le


Alicia Howell-Munson has been in the WPI PhD Program for Bioinformatics and Computational Biology since the fall of 2019. Her research interest has been to develop computers that are more intuitive and streamlined with the intent of the user. She is currently working under Professor Erin Solovey on a National Science Foundation grant for adaptive learning environments using non-invasive neuroimaging.

Alicia Howell-Munson

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Photo of Alicia Howell-Munson

Our Students' Experience

As a freshman, I felt very welcomed by previous alumni that were part of the BCB program, and gained quick support through the advisors in the department.
You can do genetic data analysis, simulations, computational methods of finding new algorithms for mathematical formulas. You can branch out even further and do analysis of brain data and map machine learning algorithms to it. I like how versatile it is
The research opportunities that span across the computer science, mathematics, and biology departments are wonderful opportunities for BCB students to recognize their specific strengths over time and gives flexibility in expanding their interests.



average starting salary, bachelor's degree

WPI Class of 2020

of master’s and PhD recipients are employed or continuing their studies shortly after graduation (2018)


best career placement

The Princeton Review (2019)
Top 5.2%

worldwide out of 20,000 universities 

Center for World University Rankings (2019-2020)

Our Faculty

Professor Amity Manning

Professor Manning is an assistant professor for the Department of Biology & Biotechnology. The work in her lab focuses on defining the cellular mechanisms that maintain genome stability in normal cells and understanding how these pathways are corrupted in cancer cells. She looks forward to working with students both in class and in the lab to gain a better understanding of cancer cell biology and to make meaningful contributions to cancer research.

Professor Amity Manning

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Professor Amity Manning

Professor Reeta Rao

Professor Rao is the associate dean of graduate studies and a professor in the department of Biology & Biotechnology. In addition to teaching students in the class setting, she has a research program that focuses on understanding and managing fungal diseases. In the program, Professor Rao mentors and works with students in her lab to employ a myriad of molecular, genetic, genomic, biochemical approaches to understand fungal pathogenesis. Her paper was recently published in Nature Communications, Volume 10. 

Professor Reeta Rao

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Professor Reeta Rao

BCB Program News

Eric Young and colleagues publish article in Nature Communications "Engineered yeast genomes accurately assembled from pure and mixed samples."

A message from Dmitry Korkin
Director, Bioinformatics & Computational Biology

We designed WPI’s BCB Program to educate students to feel comfortable in the language, concepts, and techniques of three distinct disciplines: biology, mathematics, and computer science.  We also developed courses that overlap two or more of these disciplines, each centered on different aspects of the theories, concepts, techniques, and tools of bioinformatics and computational biology.  This interdisciplinary training is exciting and rewarding, and allows students many opportunities to tackle challenging biological problems.

Graduate Highlights

Alyssa Tsiros

WPI Graduate Student Impresses at Dublin Conference

BCB graduate student Alyssa Tsiros won an honorable mention at the Symposium on Biological Data Visualization in Dublin, Ireland, for her biovisualization depicting the evolution of noncoding RNA in the Human accelerated region 1, a recently discovered gene that may be responsible for  the accelerated brain development of humans compared to other mammals. Tsoris’s project stood out for effectively using color-coded arc diagrams to depict genetic data. 

Finding Patterns that Can Improve Sleep

With their robust cross-disciplinary knowledge and hands-on project experiences, BCB graduates are well prepared for rewarding careers across a wide variety of industries. Our graduates assume leadership roles in positions in federal and state government, higher education, research and development, and the pharmaceutical industry. The average starting salary in 2015 was $66,500.

Career Outlook

With their robust cross-disciplinary knowledge and hands-on project experiences, BCB graduates are well prepared for rewarding careers across a wide variety of industries. Our graduates assume leadership roles in positions in federal and state government, higher education, research and development, and the pharmaceutical industry. The average starting salary in 2019 was $64,100.


average starting salary, bachelor's degree

WPI Class of 2020

Best Career Services

The Princeton Review (2019)

25 colleges where grads have the highest earning potential

CNBC (2018)

Best Schools for Internships

Princeton Review (2020)

Media Coverage

The National Interest talked to Dmitry Korkin, associate professor of computer science, about how and why diseases, like coronavirus spread quickly on ships.

The Boston Herald reported on the research that Dmitry Korkin, associate professor of computer science, is doing to project how viruses, including the coronavirus, might spread in confined spaces.

  • WPI scientists are using visualization tools and mixed reality to explore complex biological networks, a depiction of a system of linkages and connections so complex and dense it’s been dubbed the “hairy ball.” Dmitry Korkin, PhD, associate professor of computer science and director of the university’s bioinformatics and computational biology program, leads the research team.