BIOLOGY & BIOTECHNOLOGY SEMINAR:
"Formation and germination of spores by the bacterial pathogen Clostridium difficile”
Dr. Aimee Shen, Ph.D.
Assistant Professor of Molecular Biology & Microbiology
Host: Assistant Professor Scarlet Shell
Abstract: Clostridium difficile is a Gram-positive, spore-forming pathogen that is a leading cause of antibiotic-associated diarrhea worldwide. The metabolically dormant spore form of C. difficile is critical to its infection cycle, since it is the infectious particle of this obligate anaerobe. As a result, spore germination is essential for C. difficile to initiate infection, and spore formation is essential for C. difficile to survive exit from the host. This seminar will focus on our analyses of spore assembly, specifically formation of the protective coat layer, and the signaling cascade that leads to spore germination.
Tuesday, November 15, 2016